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Our Four Years of Paediatric Sepsis Treatment with Hemoadsorption, Albumin and Heparin: Let's Give it a Chance in Multifactorial Pathological Conditions | Chapter 14 | New Frontiers in Medicine and Medical Research Vol. 14

In the realm of intensive care medicine, extracorporeal blood purification techniques are becoming more common. These methods are used in a variety of clinical settings, including Sepsis, Trauma, Burns, Influenza, Surgery, Pancreatitis, ARDS, Life Support, and Liver Failure. New adsorptive procedures have shown to directly target the inflammatory cascade by effectively removing important mediators, as opposed to filtration-based methods commonly utilised for renal replacement treatment. However, in the neonatal and paediatric population, these approaches provide a number of hurdles as well as significant technological difficulties. A promising extracorporeal device for cystic fibrosis was recently developed. However, there is a scarcity of data on its use in severely unwell children [1]. Due to a lack of data and procedure protocols, we had to make some aprioristic diagnostic and speculative decisions based solely on science: "in primis," when we decided to use this "Cytosorb Absorber," a device not registered and delivered for toddlers, for the first time in a paediatric patient; second, when it became clear that we could extend its use to non-conventional disease therapeutic strides. The scientific community will be interested in these findings, but more investigation is required.


Author (S) Details

Milella Leonardo
Pediatric Department of Anaesthesia and Intensive Care Unit (General and Post Cardiac Surgery), Giovanni XXIII Hospital - Policlinico di Bari, Bari, Italy.

Cito Fabiana
Pediatric Department of Anaesthesia and Intensive Care Unit (General and Post Cardiac Surgery), Giovanni XXIII Hospital - Policlinico di Bari, Bari, Italy.

Raimondo Pasquale
Department of Anaesthesia and Intensive Care (Cardiac Surgery Unit), Policlinico di Bari, Bari, Italy.

Ficarella Maria Teresa
Pediatric Department of Anaesthesia and Intensive Care Unit (General and Post Cardiac Surgery), Giovanni XXIII Hospital - Policlinico di Bari, Bari, Italy.

Moliterni Paola
Pediatric Department of Anaesthesia and Intensive Care Unit (General and Post Cardiac Surgery), Giovanni XXIII Hospital - Policlinico di Bari, Bari, Italy.

Sisto Michele
Pediatric Department of Anaesthesia and Intensive Care Unit (General and Post Cardiac Surgery), Giovanni XXIII Hospital - Policlinico di Bari, Bari, Italy.

Lasorella Maria Luigia
Pediatric Department of Anaesthesia and Intensive Care Unit (General and Post Cardiac Surgery), Giovanni XXIII Hospital - Policlinico di Bari, Bari, Italy.

Lombardi Nadia
Department of Anaesthesia and Intensive Care, University of Foggia, OO RR, Foggia, Italy.

Maldera Milena
Department of Anaesthesia and Intensive Care, School of Medicine - Milano Bicocca, Milano, Italy.

Calabrese Gerolmina
Pediatric Department of Anaesthesia and Intensive Care Unit (General and Post Cardiac Surgery), Giovanni XXIII Hospital - Policlinico di Bari, Bari, Italy.


View Book :- https://stm.bookpi.org/NFMMR-V14/article/view/3396


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