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The Inflammasomes: Revamping Periodontal Pathogenesis | Chapter 3 | New Frontiers in Medicine and Medical Research Vol. 7

The discovery of inflammasomes, which are thought to govern the host immuno-inflammatory responses, has baffled the medical community recently. They are thought to serve a variety of purposes throughout the process, many of which are still unknown. Certain sensor proteins have been found to be essential for the assembly of inflammasomes in response to microbial components known as PAMPs (pathogen associated molecular patterns) or endogenous chemicals known as DAMPs (damage associated molecular patterns). Inflammasomes have been shown to activate in two phases in the majority of cases. Furthermore, according to study, this involves a variety of sensor protein families that have a role in the development of a variety of diseases, including periodontal disease, via a variety of pathways. As a result, this piece of information allows us to go deeper and look for novel targets to modify host responses to microbial challenges.


Author (S) Details

Nazreen Ansari
Department of Periodontics, Annoor Dental College & Hospital, Muvattupuzha, Ernakulam, Kerala, India.

Jose Paul
Department of Periodontics, Annoor Dental College & Hospital, Muvattupuzha, Ernakulam, Kerala, India.

Johnson Prakash D’Lima
Department of Periodontics, Annoor Dental College & Hospital, Muvattupuzha, Ernakulam, Kerala, India.

Senny Thomas Parackal
Department of Periodontics, Annoor Dental College & Hospital, Muvattupuzha, Ernakulam, Kerala, India.

View Book :- https://stm.bookpi.org/NFMMR-V7/article/view/3216

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